Applied Therapeutics Inc (OQ:APLT)

Sector:  Healthcare Industry:  Biotechnology & Medical Research
 
See Regulatory Filings on SEC
Company Contact
Address: 545 FIFTH AVENUE, SUITE 1400
NEW YORK NY 10017
Tel: N/A
Website: https://www.appliedtherapeutics.com
IR: See website
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Key People
Shoshana Shendelman
Chairman of the Board, President, Chief Executive Officer, Founder
Leslie D. Funtleyder
Chief Financial Officer and Principal Financial Officer, Director
Constantine Chinoporos
Chief Operating Officer and Chief Business Officer
Catherine Thorpe
Chief Accounting Officer
Dale Hooks
Chief Commercial Officer
Riccardo Perfetti
Chief Medical Officer
Business Overview
Applied Therapeutics, Inc. is a clinical-stage biopharmaceutical company. It is focused on developing a pipeline of novel drug candidates against validated molecular targets in indications of high unmet medical need. The Company's lead drug candidate, govorestat, is a novel central nervous system penetrant Aldose Reductase Inhibitor (ARI) for the treatment of central nervous system (CNS) rare metabolic diseases, including Galactosemia, Sorbitol Dehydrogenase (SORD) Deficiency, and PMM2-CDG. The Company is also developing AT-001, a novel potent ARI, for the treatment of Diabetic Cardiomyopathy (DbCM) a fatal fibrosis of the heart. It has completed a Phase I/II clinical trial evaluating AT-001 in approximately 120 patients with type 2 diabetes, in which no drug-related adverse effects or tolerability issues were observed. The preclinical pipeline also includes AT-003, an ARI designed to cross through the back of the eye when dosed orally, for the treatment of Diabetic retinopathy.
Financial Overview
For the fiscal year ended 31 December 2023, Applied Therapeutics Inc revenues increased from $0K to $10M. Net loss increased 45% to $119.8M. Revenues reflect an increase in demand for the Company's products and services due to favorable market conditions. Higher net loss reflects Change in fair value of warrant liabilit increase from $66K to $56.6M (expense), Operating Lease Cost increase of 3% to $505K (expense).
Employees: 25 as of Dec 31, 2023
Reporting Currency: U.S. Dollars
Enterprise value: $416.81M as of Dec 31, 2023
Annual revenue (TTM): $9.99M as of Dec 31, 2023
EBITDA (TTM): -$64.53M as of Dec 31, 2023
Net annual income (TTM): -$119.76M as of Dec 31, 2023
Free cash flow (TTM): -$55.17M as of Dec 31, 2023
Net Debt Last Fiscal Year: N/A
Shares outstanding: 105,886,831 as of Mar 5, 2024
TTM: Trailing Twelve Months
EBITDA: Earnings Before Interest, Taxes, Depreciation, & Amortization

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