Olema Pharmaceuticals Inc (OQ:OLMA)

Business Focus: Biotechnology & Medical Research

Sector:  Healthcare Industry:  Biotechnology & Medical Research
 
See Regulatory Filings on SEC
Company Contact
Address: 780 Brannan Street
SAN FRANCISCO CA 94103
Tel: N/A
Website: https://olema.com
IR: See website
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Key People
Sean P. Bohen
President, Chief Executive Officer, Director
Shane Kovacs
Chief Operating and Financial Officer
John B. Moriarty
Executive Vice President, Chief Legal Officer and Secretary
David C. Myles
Chief Discovery and Non-Clinical Development Officer
Naseem Zojwalla
Chief Medical Officer
 
Business Overview
Olema Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on the discovery, development, and commercialization of targeted therapies for women's cancers. Its lead product candidate, OP-1250, is an oral therapy with combined activity as both a complete estrogen receptor (ER) antagonist (CERAN) and a selective ER degrader (SERD). The Company's OP-1250 is an oral small molecule clinical-stage product candidate for the treatment of endocrine-driven cancers. OP-1250, both as a monotherapy and in combination with inhibitors of cyclin-dependent kinase four and six (CDK4/6) demonstrated robust tumor shrinkage in several xenograft models, including ESR1 and PIK3CA mutations and central nervous system (CNS), metastasis. It is in the Phase I/ II clinical trial, and in Phase Ib/ II combination with palbociclib, in patients with metastatic ER-positive (ER+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer.
Financial Overview
For the fiscal year ended 31 December 2023, Olema Pharmaceuticals Inc revenues was not reported. Net loss decreased 8% to $96.7M. Lower net loss reflects Interest income increase from $2.2M to $8.3M (income), General and administrative - Balancing decrease of 27% to $13.3M (expense), Stock-based Compensation in SGA decrease of 14% to $5.5M (expense). Basic Earnings per Share excluding Extraordinary Items increased from -$2.62 to -$2.14.
Employees: 74 as of Dec 31, 2023
Reporting Currency: U.S. Dollars
Enterprise value: $290.07M as of Dec 31, 2023
Annual revenue (TTM): $0.00M as of Dec 31, 2023
EBITDA (TTM): -$104.58M as of Dec 31, 2023
Net annual income (TTM): -$96.66M as of Dec 31, 2023
Free cash flow (TTM): -$83.73M as of Dec 31, 2023
Net Debt Last Fiscal Year: N/A
Shares outstanding: 55,914,741 as of Mar 7, 2024
TTM: Trailing Twelve Months
EBITDA: Earnings Before Interest, Taxes, Depreciation, & Amortization

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