Denali Therapeutics Inc (OQ:DNLI)
Business Focus: Bio Therapeutic Drugs
| Sector: Healthcare | Industry: Biotechnology & Medical Research |
| See Regulatory Filings on SEC | |
| Company Contact | |
| Address: | 161 Oyster Point Blvd SOUTH SAN FRANCISCO CA 94080-1910 |
| Tel: | N/A |
| Website: | https://www.denalitherapeutics.com |
| IR: | See website |
| Key People | ||
| Ryan J. Watts President, Chief Executive Officer, Director | Alexander O. Schuth Chief Financial Officer, Chief Operating Officer, Company Secretary | Carole Ho Chief Medical Officer |
| Business Overview |
| Denali Therapeutics Inc. is a biopharmaceutical company. The Company is focused on developing a portfolio of product candidates engineered to cross the blood-brain barrier (BBB) for neurodegenerative diseases and lysosomal storage disease. The Company has a portfolio of both small molecule and biotherapeutic medicines, comprising seven product candidates in clinical development across seven indications as well as preclinical therapeutic candidates. Its three late-stage development programs include tividenofusp alfa (DNL310) for mucopolysaccharidosis II (MPS II); BIIB122/DNL151 (LRRK2 inhibitor) for Parkinson's disease; and DNL343 (eIF2B activator) for amyotrophic lateral sclerosis (ALS). SAR443820/DNL788 (RIPK1 inhibitor) is being evaluated in a Phase II study for multiple sclerosis (MS). In addition, it has a Phase I/II study of TAK-594/DNL593 for frontotemporal dementia-granulin (FTD-GRN) and a Phase I/II study of DNL126 for MPS IIIA (Sanfilippo syndrome). |
| Financial Overview |
| For the three months ended 31 March 2024, Denali Therapeutics Inc revenues decreased from $35.1M to $0K. Net loss decreased 7% to $101.8M. Revenues reflect a decrease in demand for the Company's products and services due to unfavorable market conditions. Lower net loss reflects Research & Development Expense - Balanci decrease of 19% to $90.7M (expense), Interest income (expense), net increase of 44% to $15.9M (income), Selling. |
| Employees: | 375 as of Mar 31, 2024 |
| Reporting Currency: | U.S. Dollars |
| Enterprise value: | $1,674M as of Mar 31, 2024 |
| Annual revenue (TTM): | $295.39M as of Mar 31, 2024 |
| EBITDA (TTM): | -$199.30M as of Mar 31, 2024 |
| Net annual income (TTM): | -$137.25M as of Mar 31, 2024 |
| Free cash flow (TTM): | -$425.11M as of Mar 31, 2024 |
| Net Debt Last Fiscal Year: | N/A |
| Shares outstanding: | 142,609,036 as of Apr 30, 2024 |
| TTM: Trailing Twelve Months EBITDA: Earnings Before Interest, Taxes, Depreciation, & Amortization | |
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