Ionis Pharmaceuticals Inc (OQ:IONS)

Business Focus: Biotechnology & Medical Research

Sector:  Healthcare Industry:  Biotechnology & Medical Research
 
See Regulatory Filings on SEC
Company Contact
Address: 2855 Gazelle Court
CARLSBAD CA 92010
Tel: N/A
Website: https://www.ionispharma.com
IR: See website
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Key People
Brett P. Monia
Chief Executive Officer, Director
Elizabeth L. Hougen
Chief Financial Officer, Executive Vice President - Finance
C. Frank Bennett
Executive Vice President, Chief Scientific Officer
Joseph T. Baroldi
Executive Vice President, Chief Business Officer
Richard S. Geary
Executive Vice President, Chief Development Officer
Kyle Jenne
Executive Vice President - commercial
Eugene Schneider
Executive Vice President, Chief Clinical Development Officer
Eric E. Swayze
Executive Vice President - Research
Patrick R. O'Neil
Chief Legal Officer, General Counsel and Corporate Secretary
Business Overview
Ionis Pharmaceuticals, Inc. is engaged in ribonucleic acid (RNA)-targeted therapeutics. The Company has five marketed medicines and a pipeline in neurology, cardiology, and other areas of high patient need. It has nine medicines in Phase III development and multiple additional medicines in early and mid-stage development. The Company's products include SPINRAZA, QALSODY, WAINUA, TEGSEDI and WAYLIVRA. SPINRAZA is used for the treatment of patients with spinal muscular atrophy (SMA), a progressive, debilitating and often fatal genetic disease. QALSODY is an antisense medicine that is used for the treatment of adult patients with superoxide dismutase 1 amyotrophic lateral sclerosis (SOD1-ALS), a rare, neurodegenerative disorder that causes progressive loss of motor neurons leading to death. WAINUA is a self-administered subcutaneous LIgand-Conjugated Antisense (LICA) medicine used for the treatment of adults with polyneuropathy of hereditary transthyretin-mediated amyloidosis (ATTRv-PN).
Financial Overview
For the fiscal year ended 31 December 2023, Ionis Pharmaceuticals Inc revenues increased 34% to $787.6M. Net loss increased 36% to $366.3M. Revenues reflect Collaborative agreement revenue increase of 70% to $352.7M, WAINUA joint development revenue increase of 65% to $126.4M, Other commercial revenue increase from $31M to $68.2M. Higher net loss reflects Gain (loss) on sale of real estate asset decrease from $149.6M (income) to $161K (expense).
Employees: 927 as of Feb 15, 2024
Reporting Currency: U.S. Dollars
Enterprise value: $5,130M as of Dec 31, 2023
Annual revenue (TTM): $787.65M as of Dec 31, 2023
EBITDA (TTM): -$340.88M as of Dec 31, 2023
Net annual income (TTM): -$366.29M as of Dec 31, 2023
Free cash flow (TTM): -$331.32M as of Dec 31, 2023
Net Debt Last Fiscal Year: N/A
Shares outstanding: 145,751,797 as of Feb 15, 2024
TTM: Trailing Twelve Months
EBITDA: Earnings Before Interest, Taxes, Depreciation, & Amortization

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